This article was review by Thomas Cooper, MD from Baylor College of Medicine. Stay up to date on the latest science with Brush Up Summaries. Despite its significance, alternative splicing’s global ...
In eukaryotic genetics, the one-gene/one-protein concept has, for the most part, breathed its last. Researchers have rallied behind mechanisms such as alternative splicing, which may allow a lowly ...
Take a genomic eukaryotic sequence, match it with a mature eukaryotic mRNA or a reverse-translated protein sequence, and you’ll discover the location of introns. These, of course, are spliced out ...
Although the participation of spliceosomes is almost always required for intron removal, a few types of genes have ...
The student will investigate how protein arginine methylation, a type of post-translational modification commonly found in RNA-binding proteins, regulates the function of an evolutionarily conserved ...
A new study points to introners, one of several proposed mechanisms for the creation of introns, as an explanation for the origins of most introns across species. One of the most long-standing, ...
An international collaboration between four senior scientists from Mainz, Valencia, Madrid, and Zurich has published groundbreaking research in the journal PNAS, shedding light on the most significant ...
Researchers at the Centre for Genomic Regulation (CRG) have created the first blueprint of the human spliceosome, the complex molecular machine that edits genetic messages transcribed from DNA, ...
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