Morning Overview on MSN

RNA strand that nearly self-replicates could unlock life’s origin

A 45-nucleotide strand of RNA can now synthesize both its mirror-image complement and a copy of itself, bringing scientists ...

RNA is key to the dark matter of the genome − scientists are sequencing it to illuminate human health and disease

Researchers are embarking on the RNA equivalent of the Human Genome Project, including sequencing all the chemical ...
EurekAlert!

Cross-chiral exponential amplification of an RNA enzyme (IMAGE)

Salk scientists engineered a right-handed RNA enzyme (bottom left) that can combine left-handed RNA fragments (bottom right) to create a mirror image of itself. The new left-handed RNA enzyme (top ...

Tiny, 45 base long RNA can make copies of itself

These random molecules were fed a collection of three-base-long RNAs, each linked to a chemical tag. The idea was that if a molecule is capable of ligating one of these short RNA fragments to itself, ...
EurekAlert!

Stylized image of an RNA thermometer (IMAGE)

Stylized illustration of an RNA thermometer in the gene lpxP, identified in E. coli and conserved across various bacterial species. On the left, the OFF conformation. The Ribosome Binding Site (RBS, ...
Pharmaceutical Technology on MSN

RNA-targeting small molecules: a new frontier of drug discovery

With big pharma signalling interest in novel RNA-targeted approaches, the term “druggable” is being redefined as technology advances.