Simultaneous measurement of dozens of types of fats in the blood ("lipidomics") can predict the risk of developing type 2 diabetes (T2D) and cardiovascular disease (CVD) years in the future, according ...

With the aging of the global population, the prevalence of metabolic diseases has significantly increased over the past two decades. Meanwhile, China grapples with the largest population aged 65 years ...

Impact of race on BluePrint genomic subtyping in HER2+ breast cancer. Performance of the lipid signature assessed from extracellular vesicles and plasma across patient cohorts. Stage I-IV IDC (n=44) ...

Design of phase Ib/II study of oral VERU-111, an α and β-tubulin inhibitor, for the treatment of metastatic castration- and androgen-blocking-agent-resistant prostate cancer. Background: Altered lipid ...

Elevated deoxycholic acid, triacylglycerols, ceramides, and phospholipids were identified in MASH patients, suggesting a noninvasive diagnostic potential. The study used untargeted lipidomic analysis ...

Pemvidutide is a novel, investigational, peptide-based GLP-1/glucagon dual receptor agonist in development for the treatment of obesity and MASH. Activation of the GLP-1 and glucagon receptors is ...

An international team of scientists has developed a method for simultaneously detecting thousands of lipid molecules that are displayed to T cells in the human immune system. The study, co-led by D.

The lipids in biological systems used to be seen as little more than energy reservoirs and insulating materials. Then they were found to serve additional functions. Lipids were identified as chemical ...

This study mapped how EPA and DHA are distributed across lipid classes in microalgae, fish, krill, and commercial omega-3 ...