Dallas, TX - A team of biochemists has elucidated the 3-dimensional structure of a low-density lipoprotein (LDL) receptor during 1 stage of the process in which it releases LDL. The discovery may aid ...
Lipoprotein(a) is a presumed risk factor for atherosclerotic cardiovascular disease. Olpasiran is a small interfering RNA that reduces lipoprotein(a) synthesis in the liver. We conducted a randomized, ...
In a recent study published in the journal Current Medical Research and Opinion, researchers report that high lipoprotein(a) levels were linked to repeated coronary heart disease events in older ...
Lipoprotein (a) is a low-density lipoprotein that transports cholesterol in the blood. The lipoprotein (a) test — or Lp(a) test — determines the level of this lipoprotein in the blood, and its results ...
High-density lipoprotein—the so-called good cholesterol—plays an important role in reducing the risk of heart disease. Despite its importance, all structural information has come from synthetic HDL ...
Evolocumab, a monoclonal antibody that inhibits proprotein convertase subtilisin–kexin type 9 (PCSK9), significantly reduced low-density lipoprotein (LDL) cholesterol levels in short-term studies. We ...
Brigham and Women's Hospital investigators link very high lipoprotein(a) with a higher 30-year risk of major cardiovascular events in initially healthy women. Elevated plasma lipoprotein(a) is a ...
Unlike LDL, cholesterol which most people are aware of, Lp (a) is a genetic form of cholesterol that is mainly not impacted by our lifestyle or diet. Lp (a) is carried within us in blood and can cause ...