A recent study confirms lenacapavir's effectiveness against HIV and highlights the capsid as a promising drug target despite resistance.
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Study reveals previously unknown role for viral protein integrase in HIV's life cycle
The tiny shell protecting the HIV virus resembles a slightly rounded ice cream cone, but there is nothing sweet about it.
Coarse-grained simulations of HK97 genome packaging. A motor protein pushes DNA through a portal into the capsid, where the DNA coils into switchback loops. DNA is colored in order of entry into the ...
Researchers revealed that HIV integrase forms structural filaments within the viral capsid, enabling viral infectivity. The ...
From a virus's point of view, invading our cells is a matter of survival. The virus makes a living by highjacking cellular processes to produce more of the proteins that make it up. From our point of ...
New research from the University of Minnesota School of Dentistry and Masonic Cancer Center is providing important new insights into the structure of a human virus that causes blood cancer. In their ...
Because viruses have to hijack someone else’s cell to replicate, they’ve gotten very good at it—inventing all sorts of tricks. A new study from two University of Chicago scientists has revealed how ...
New research from the University of Minnesota School of Dentistry and Masonic Cancer Center is providing important new insights into the structure of ...
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