The brain's ability to do everything from forming memories to coordinating movement relies on its cells producing the right proteins at the right time. But directly measuring this protein production, ...
A study using Ribo-STAMP technology reveals that protein production in brain cells varies significantly between different types of neurons, offering new insights into autism and memory.
mRNA sequences affect translation efficiency (IMAGE) University of Texas at Austin Caption Subtle differences in an mRNA sequence enables a ribosome to produce more or less of a certain protein. A new ...
Add Yahoo as a preferred source to see more of our stories on Google. New AI model predicts mRNA protein output, aiding drug and vaccine design by targeting specific cells. (CREDIT: Science Photo ...
In a recent review published in Nature Medicine, researchers presented challenges related to the clinical translation of messenger ribonucleic acid (mRNA) technology, recent innovations, and future ...
Research led by Duke University, Durham, has discovered a situation-dependent traffic jam in mRNA translation caused by RNA hairpins leading to higher translation of upstream start codons (uAUGs). In ...
In a recent study published in Nature, a group of researchers explored how the incorporation of N1-methylpseudouridine (1-methylΨ) into messenger ribonucleic acids (mRNAs) affects ribosomal ...
Neurodegenerative diseases are commonly adult-onset conditions characterized by degeneration of specific neuronal populations. Familial forms are caused by mutations in single genes, but most patients ...
Fig. 2 Examples of ionizable lipids, sterols, phospholipids, and PEG-lipids used in LNP formulations. Created with BioRender.com. Fig. 3 High-throughput screening of the 3-component ionizable ...
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